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Peer-Reviewed ResearchClark et al. · Plastic and Reconstructive Surgery — Global Open · 2026

Understanding Capsular Contracture: Mechanisms, Management, and Patient Outcomes

A review of capsular contracture — the abnormal thickening and hardening of the scar-tissue capsule around an implant — covering how it is graded, the leading proposed mechanisms, and risk factors.

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What this source says

The review describes capsular contracture as an exaggerated fibrotic response in which the capsule hardens and can distort the breast or cause pain; it is commonly graded with the Baker scale (I–IV); leading proposed mechanisms include chronic inflammation and bacterial biofilm; and risk factors include radiation, implant surface, pocket location, and smoking.

Why it matters

A current synthesis of the most common long-term implant complication — helpful for understanding what “contracture” and “Baker grade” mean.

Key findings

  • Reported to affect roughly 5–19% of augmentation and 19–25% of reconstruction patients.
  • Graded with the Baker scale (I–IV), which the authors call subjective and practitioner-dependent.
  • Leading proposed mechanisms: chronic inflammation, bacterial biofilm, and fibroblast activation.
  • Risk factors include post-mastectomy radiation, implant surface texture, pocket location, and smoking.

Limitations

The authors note most evidence comes from retrospective cohort studies without randomized trials (a moderate-to-high risk of bias), and that Baker grading is subjective.

What this does not prove

It describes associations and proposed mechanisms; it does not establish a single proven cause of capsular contracture.

Source / citation

Clark et al. · Plastic and Reconstructive Surgery — Global Open · 2026

https://pmc.ncbi.nlm.nih.gov/articles/PMC12803722/

DOI:
10.1097/GOX.0000000000007407

Last reviewed against the original source: 2026-09-02. Summaries are written in plain language; the original source is authoritative.

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